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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059607cede31471beec5da2c4f0f0227fff3fcce52fdb5282ede15daf85dc32f' 
  AND token = 'GPN0EgPvk2M4mifoV9Z/yEbSgZSKRNAIffuRz1j4y7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}