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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e3932d42226cad1b2ca026ad4fa955c114d9b6c130551afea23d2d1a724548' 
  AND token = 'eC8JFUUqhs84QclLIPc+z2Vnu8aGSCigYbH0Ffgk8v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}