SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefa18bba3229fa9584dd899d088603ca9afc9cc27d922f463130ac2719b0ac8' 
  AND token = '+66VyC4VkhQ+056q4zI87FnXPmpn9iJ+uF7TkOzzZfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}