SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6c28e6eab8641a0d6cf60baec7ee611848027f6cff498be28356270076351f' 
  AND token = 'OvufnW8fNfSdqGT1IU+2qGghdeLWEajCqHduBejuMn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}