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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35aa2296cc5d011af86b87acaf44bfcacd809d0a4c796a03d6ea66198efcffe4' 
  AND token = '7upxJAve3TFfblsq4xvOwQw69IAHv1OJnW0WLJ0xiMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}