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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '079949fa87ab924671c98ec80985e59ca61a2e685de6f793b9b2e50809f6ab05' 
  AND token = '553uwdiYwhIFFRoTsJOZ29wmN649m53EADpdq1Xm8EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}