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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee57ebc4919daf83909c00390ed3cd3ef5792dacb1e3fa3fe3372e6d37f32f4c' 
  AND token = 'IbOrqnc00asd1yr4wrVUW9ek9n6LuwvssGmy+ba0JIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}