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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539dc1d410306cce218f2b6eaa104373710165f6e75c071c49fb6458b855ae2e' 
  AND token = 'O1rF6UVqNnyCNO14NitxUKIjTrSV2EYFH/Lge9OUwsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}