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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1a39e459ef8ec700b7138c3217f0b743007369f93b0b95dfa72b6dd2253b5b' 
  AND token = 'ZE2uQQJkYkFbFozhbsgYwys6BySYL7boc1ZL6cg7OVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}