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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09f0ce23a3d019ecdf88c202e6a574020a6553291fdd25cab823b0878c3c835' 
  AND token = '18jl1i+wHh1FLhcwvMuZYY1q97iaXuSJq58KOlUu3rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}