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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1c696caf399456a2ca25a758a6ebe00654351b5f5d6e7313ad3ee5cf3ae262' 
  AND token = '+zD2qcTVr+df/aR+EeFkMQAO0xTJPRNKa4qGEauWo8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}