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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5360c34c9275e54936add370b8a2a42632bab17a36589386ca6d1e7e6e6eda11' 
  AND token = '4jdTW6qQ41YuTTF5DitUDzgNzPD2XEwjuziDpxZ4Fqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}