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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec08afd4c7ad1af8a28ccf8da7e5c82bc46bf787476241c18481b0e4a46b124' 
  AND token = 'LMmrxZqzeTRq457JUUk8nD77rMbOGqXgyT9BK4F7Xmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}