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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446adc4d7ca09aee10cf5923edaa36a3dab1cfe728343344c7b5504ea0e61b4d' 
  AND token = 'G3BoMy+PQ78y1YL8LzhnMVLiCkI3A7hJ5ekYuALcEk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}