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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ae3d6f8c915767f5a83fea70dbb38f03d3dfe9f61a61b0ffa2b944bcf9df84' 
  AND token = 'DQfR0mNSCXUE2KlMPFvaLdgneDlr12hzsVvatTEkWK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}