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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18ad28890a0fd747cb0ed8d29b4e72d485584cf8c22ac50789e599e4193095f' 
  AND token = 'JEHFU4xSH4q2OT1PVTXo5yEbx/m2rOvJCVCbb1ogFFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}