SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f498ed2c5b91604f65e55ee4cf801e896c9232e0bf14c9185610720a76543d6c' 
  AND token = 'Ka2cNwxzQSYrfdWCEVa/c6dlsOiprAxETp9OnLYxyMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}