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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5270c24b910c43146634d039a45f4bb9bc6130b4f8f0426456a3465d874a2d3' 
  AND token = 'TAUlfiDfVgMuLdXVpN19krJoI59povDN0bCRvZD7uKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}