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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da7a45ee9839ea7ec28d817d9a790383afcdf14d0866c0c06053ad3344373127' 
  AND token = 'CMAma9cc+QUl+S9jtLgIc9xw3DvSqIc5qxLDF13jlaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}