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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea44f9f47b86984e7a05e864601e902fb2ba6700960ee690e3c829504821d52' 
  AND token = 'VRApgful5JwgVdUM2lzx9Tk2PbK0I5iyI+rKXuS8Dz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}