SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b989406a8e29a204c4f74b25731d269d2e1662664c0f1291ce486f12e3b75f' 
  AND token = '++NSHx7U8yWU2tSae1kplR+siclhQ0VKXPCm5a/FhqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}