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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcb05ab89a46a99307bf6be625e8dea5d8a714720a6f77a57092892f2d42286' 
  AND token = '/1WmtmlFMD15caCeVqBX1GEppAwzNYagm0ALha42++k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}