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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8264f560cbbd7b14a2b84d283827d4dedcdd483674cfb40da86f25c6ceaab3f' 
  AND token = 'HxkvVkJstcCIYGpq1R2HnePdHSw6obI7ZOwv59FAqdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}