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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437d4649db7e94308a3428442080f205afb7ffe53d67834a23a1eb0f1fc7ee92' 
  AND token = 'HaOmybbFGyygAz6cfIVbDRrtADUiFDOif++leQC/sj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}