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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b403e42063b1fb600d11dd4fda3cbd221a50b22aa6c656a2f3f5bdc590a712df' 
  AND token = '9OB0tpUZujVaK8e3EQL/xjktnNvYQsM4TSqWmVzRSFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}