SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801a63a905b01e3cfb82c50035e10aab50884a53908bb125f01697fcbda6fbf5' 
  AND token = 'XXyWFa2xOvRm5Yl5ejrooTbK83pawclOWaHztK6XhJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}