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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b858abad3292133e4235a68caaf30412e50c2355324fd87b794486a122beb6c' 
  AND token = 'WReAhuLXAmkpGnCR7jYA0V2j0pcfv6xyyOhYyw8iWLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}