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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c777dc8bf55f056f7c84b1e3024411a9a4af07b84f9a317f8e9ec475ff15cfd3' 
  AND token = 'Y3NcJR1xxOthjT6l3s/JaP4IV16tAzm+4esS3hRAXO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}