SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '806701af37dd0f21149383206228f136abbf67538d4b24052ddd1d0b577ab1f4' 
  AND token = 'PYdJARx4knniJFwMgMM1V5xwaPB/D3uKN2+WoheI3nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}