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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edad43e4c76d2aa5b96e1bf12b55bea5a8a971405f6719c4030f3af66f0e88b6' 
  AND token = 'EQNOKtYv87wpRO9h0rIZKgDqY5qNTD8vZ3ZWunFeq7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}