SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144bf69b05ce0503b297ec0674d0a35d563f73982cf879c726f1440e1bea5eb4' 
  AND token = 'szrAMXpO9jDROloFoMV1j30OJCFBBH+hlcksB1iLa8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}