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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54255c27a8349a39ed30a0d31329367f21cf6f961229ed268ab257daad35feed' 
  AND token = 'wi5cqrAP7rZ5eSJT4dwoFLLF3j/BMhY714mZbDNzu4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}