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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a69795ef5df954acb0a1decf022bb7552310433dbd1212c18a502a8d85b06d' 
  AND token = '50TbRFXCacpY3OzD0ugPFzQS+P0CiFYU8G3bGzH506Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}