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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800157cb9129539ae9fa4ff16af3bad153201c2353bfc59c4ddb75e53a178aea' 
  AND token = 'QqaIUPhN4VCKD10l1pXuUtF1VoxPDrh57+226IwZZ90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}