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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a74ffa0d535818f6e23037b52d560cab597bb1aca0d80c484ef4b19abe889c' 
  AND token = 'zfDGuHd2DvtVZ+TrZNdrPrzuljnGiGD/bz7/4PTsPA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}