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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9243da8705ab87fb7343c77becd53c90e410d1b147ce44bab223d2b5fc17ddb' 
  AND token = 'w2WqUy4ymO+eH8H3GKlHtWOQGKu1KapmsuDU6AW3J5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}