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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50566fc072c354273bdb4620d3d1a93167e653cd2fbc7c1b2a5275f1dcb39c1e' 
  AND token = 'Ygje9YYDz6ejUTKI5laEpJ1Qxz1XnK9245LV1QOzHU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}