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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10116bc2545fbb2782b7536e6bde2e7b4c51188e2de6e843444b937e73e110bf' 
  AND token = 'kYiF5VTo4M2D1f7MZasV8AkhK9dleYityHdztsnepZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}