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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c52f9dc7509d947cd9d465b7425b51c04bb38da14626a47b2694bc01cc1550' 
  AND token = 'vhE+W4WbyUXiUwNYagpCiyZjAkeuimkByF4I3xKLpco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}