SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a703bc97da8b977017006e1410b99db46201546630c32b38b6078b4d5a73f29f' 
  AND token = 'ayDsFniyHuYM1lZkZDWZmlrK8HzXLkToPXHLSrSOfwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}