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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19dddc58be1d2f2897742e758eaa5dddafeaaf7ad1f888ee87d17e61f4142cf' 
  AND token = 'GUbYeoIZO3EkQWc801XF9Ln8nZvQLAqMs3RqqcIPKvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}