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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e34ea4545a257c74e779b560d021628cc4263a5b4c59b140a6012a9b4390deaf' 
  AND token = 'rsZuaDq/9Ltv3rJcMgD4zGkMMbf6iCBG4SQ4Q+IiQvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}