SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1f2536d61c8f5a72b4824a5af566ee87a31ffab9313237f807e03149054a68' 
  AND token = 'aHQFGTUSsg3CWlKtlpvdNbqGSh8dDf825njhz6UAAbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}