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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162ccfdd4c7c1296872aa210f0821060b43c96f66ecc8e4c74df287f2866b917' 
  AND token = 'his8Z2pHXMmmYuOjW6xTJ6U08B2dj2ZuJL/klIMN1z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}