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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387f1b7ee1f08c808d01843555690238cc7ded8c1b64e094a26019bf6992fbec' 
  AND token = 'uQD5c8DHnleycPfAyJq1I60D75urFJOadFK+cQwjIDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}