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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '039002888ac0f03740c065f93e0f018656d59393c01d4d3d3c3e6aaad5ef4d86' 
  AND token = 'h4TZtbbY+e7CZ3g+D/Qca+oqRV5xELQlYSq0RVExxLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}