SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe67d86cae7cd5a5fc11438c17172e1753d9882a76dc0afac21ea7fd0c08ca0' 
  AND token = 'EQm8YQcV4tdf0dMWU2k5/REaeB2w/ONJnpNVoBANQNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}