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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66aace95ea498705673da998ebe1e16d0a1e809a3073df4ec077f0f85de169e' 
  AND token = 'rkBuZu5U3pA1wcR2IcIF/hBtRYDXMvz6ToMSvHkiJDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}