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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f97a12f30d3600b5df6a1e2f34a5ce49055de2b115541159f30cd46bf5012a54' 
  AND token = 'umah+TuzTse4fbKc0e6em+ThQZBj0Ir8z3NITYGEJOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}