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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de8ae396979901a54a0e5511a077865b7279364d3039039057822611492f838' 
  AND token = 'COHcfsRa+thXtUsNFDxGSjK0+7tb4J7Y9U+fXoDdzPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}